for a great door and effectual is opened unto me, and there are many adversaries.

For a great and important door there is open to me, and there are a number of people against me.

διοτι ηνοιχθη εις εμε θυρα μεγαλη και ενεργητικη, και ειναι πολλοι εναντιοι.

For a great door and effectual is opened unto me, and there are many adversaries.